Pseudothrombocytopenia due to platelet aggregates in an infant: A case report

Autores/as

  • Esteban Artunduaga-Cañas Unidad Central del Valle del Cauca-UCEVA, Colombia
  • Esteban Pineda Arias Unidad Central del Valle del Cauca-UCEVA, Colombia
  • Estefania Rivera Velásquez Unidad Central del Valle del Cauca-UCEVA, Colombia
  • Juan Sebastián Arango Duque Unidad Central del Valle del Cauca-UCEVA, Colombia
  • Juan Diego Rivera Villota Unidad Central del Valle del Cauca-UCEVA, Colombia
  • Diego Fernando López Muñoz Unidad Central del Valle del Cauca-UCEVA, Colombia

DOI:

https://doi.org/10.54502/msuceva.v3n2a3

Palabras clave:

Ethylenediaminetetraacetic acid (EDTA), autoantibodies, platelet aggregation, Pseudothrombocytopenia, thrombocytopenia

Resumen

This case report describes the finding of EDTA-dependent Pseudothrombocytopenia in an 8-month-old infant, an extremely rare condition not reported in the literature. The patient presented with a fever due to insect bite and was diagnosed with abscessed cellulitis. A complete blood count showed a thrombocytopenia of 47 mil/L, with no history of bleeding or hematologic disease. The following day a new test was performed, which showed a platelet count of 214 mil/L, which was not consistent with the expected evolution of a real thrombocytopenia. Pseudothrombocytopenia was suspected and confirmed by observing platelet aggregates in the blood smear and upon recounting in a tube with sodium citrate, showed a normal value of 298 mil/L. Treatment consists of avoiding the use of EDTA as an anticoagulant and using other anticoagulants such as citrate or heparin. Timely identification of this phenomenon is essential to avoid diagnostic confusion and unnecessary or harmful treatment. This case brings to the scientific literature an example of EDTA-dependent Pseudothrombocytopenia in a pediatric patient, which can be easily confused with other causes of thrombocytopenia and requires a high index of clinical suspicion.

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Biografía del autor/a

Esteban Artunduaga-Cañas, Unidad Central del Valle del Cauca-UCEVA, Colombia

Fifth year medical student at the Unidad Central del Valle del Cauca, Colombia. Passionate about research in haematology, surgery and internal medicine. I am a member of the Centre for Research in Communicableu Infectious Diseases (EINTRANS) of the Department of the Faculty of Health, with national and institutional recognition in research.

Esteban Pineda Arias, Unidad Central del Valle del Cauca-UCEVA, Colombia

Fourth year medical student at the Unidad Central del Valle del Cauca, Colombia. I am a member of the Communicable Diseases Research Centre (EINTRANS) in the Department of Health Sciences of the UCEVA. My focus is to actively participate in research projects in this field, contributing to the advancement of knowledge in the field of medicine.

Estefania Rivera Velásquez, Unidad Central del Valle del Cauca-UCEVA, Colombia

Fifth year medical student at the Unidad Central del Valle del Cauca UCEVA, Colombia. I am passionate about research and analysing issues, and my goal is to actively participate in research projects that contribute to the development of medicine and science.

Diego Fernando López Muñoz, Unidad Central del Valle del Cauca-UCEVA, Colombia

Professor at the Faculty of Health Sciences of the Central Unit of Valle del Cauca, Colombia. Bacteriologist of the Catholic University of Manizales. MsC in Biomedical Sciences from the University of Castilla-La Mancha, Spain and Specialist in Transfusion Medicine from the Autonomous University of Barcelona, Spain. He is currently the director of the Research Group on Communicable Infectious Diseases - ENITRANS.

 

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Publicado

2023-12-01

Cómo citar

1.
Artunduaga-Cañas E, Pineda Arias E, Rivera Velásquez E, Arango Duque JS, Rivera Villota JD, López Muñoz DF. Pseudothrombocytopenia due to platelet aggregates in an infant: A case report . Magna Sci. UCEVA [Internet]. 1 de diciembre de 2023 [citado 21 de junio de 2024];3(2):143-9. Disponible en: http://revistas.uceva.edu.co/index.php/magnascientia/article/view/83

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Sección

Medicina (Medicine)

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